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Amino Acids Analysis
NUTRITIONAL ASSESSMENTS

The Amino Acids Analysis (Urine or Plasma) is an invaluable tool for evaluating dietary protein adequacy and assimilation, as well as metabolic imbalances underlying many chronic disorders. With the precise results and comprehensive commentary provided, nutritional deficits, metabolic impairments, and amino acid transport disorders can be accurately identified and corrected.
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WHAT DO DEPRESSION, HEART DISEASE, AND DETOXIFICATION IMPAIRMENTS ALL HAVE IN COMMON?

The answer lies in their association with amino acid imbalances. Low tyrosine or phenylalanine can result in abnormal levels of mood-regulating dopamine and catecholamines. Low taurine or high homocysteine have been associated with cardiovascular problems. And low levels of methionine, glycine, and glutathione (among others) can result in compromised clearance of toxic substances from the body.

Great Smokies' Amino Acids Analysis is a quick and convenient means of getting to the root of some of these chronic disorders. Our report form provides levels of over 40 analytes. Problem areas are targeted, such as dietary inadequacy (or malabsorption) of essential amino acids, insufficiencies of particular vitamins or mineral cofactors required in amino acid metabolism, and susceptibility toward particular diseases.

Precise results make possible specific nutritional intervention, resulting in improved clinical outcomes. Amino acids are essential to life. In free form or linked as peptides they assume important roles in such activities as neurotransmitter function, pH regulation, cholesterol metabolism, pain control, detoxification, and control of inflammation. Amino acids com-prise the building blocks of the pro-teins found in structural tissues of the body. In fact, the word "protein" derives from the Greek "protos," meaning "first," a designation underscoring its prominence.

The various functions supported by amino acids in the body depend upon prop-er amino acid metabolism. Metabolic impairments are hidden in many individuals. These impairments may be expressed as subtle symptoms or overt diseases. Amino acids analysis should be considered whenever a thorough nutritional and metabolic workup is desired for an individual. In addition to family history, a variety of conditions may alert the practitioner to the possibility of disordered amino acid metabolism, including chronic fatigue, frequent headaches, chronic gastrointestinal distress, intolerances to foods and chemicals, persis-tent inflammatory responses, depression, learning disabilities, malnutrition, neurological disorders, or symptoms of degenerative disease.

Why Is This Test Important

Amino acids are the building blocks that make up protein in all bodily tissues, including bone, muscles, ligaments, tendons, nails, hair, glands and organs. Amino acids are also the basic constituents of all hormones, enzymes and neurotransmitters.

Assessment of amino acid levels will help to identify contributors to illness and allow for precise replacement of deficient amino acids.

Because various vitamins and minerals are used as cofactors in amino acid metabolism, imbalances in amino acids noted on the test report can also point to insufficiencies of some of these cofactor nutrients.

Inborn dysfunctions of metabolism, such as phenylketonuria (PKU) or cystinuria, may be revealed by this profile.

WHAT DOES THIS TEST INVOLVE?

This test can either be performed on a 24-hour urine collection or a fasting plasma specimen.

The Urine and Plasma Amino Acid Analysis reports consist of 44 and 43 individual metabolites, respectively. A Urine or Plasma "Representativeness" index provides a quick measurement of reliability of the specimen for testing.

The report includes detailed commentary on abnormal findings, a "Supplement Schedule" which lists recommended replacement amounts of the subnormal amino acids, and an "Interpretation At A
Glance" which suggests the likelihood of imbalances in the various systems as well as insufficiencies of the nutrient cofactors.

WHAT ARE THE CONSEQUENCES OF AMINO ACID IMBALANCES?
Because amino acids are involved in every bodily system, deficiencies or imbalances in these compounds can lead to disorders of behavior and mood, digestion and absorption, hormone balance, cardiovascular function, detoxication, oxidative stress, pH regulation, and the musculoskeletal system.
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